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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
9.7
Human Site:
S294
Identified Species:
15.24
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
S294
T
S
A
T
D
I
S
S
A
G
S
I
S
G
D
Chimpanzee
Pan troglodytes
XP_511025
426
45548
G279
P
G
S
A
E
V
Q
G
M
A
G
P
A
A
E
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
S294
T
S
A
T
E
I
S
S
A
G
S
I
S
G
D
Dog
Lupus familis
XP_853833
304
33793
I256
D
L
S
S
A
G
S
I
S
G
D
I
I
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
S284
T
P
A
A
E
V
S
S
G
S
I
S
G
D
I
Rat
Rattus norvegicus
Q62814
300
33206
D255
S
S
G
S
I
S
G
D
I
I
D
E
L
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
G181
T
P
S
G
A
I
S
G
D
I
I
D
E
L
M
Chicken
Gallus gallus
Q90977
403
43534
H353
S
M
D
T
L
L
E
H
G
K
D
D
F
P
G
Frog
Xenopus laevis
NP_001086706
375
40890
T256
A
E
S
Q
D
C
P
T
G
Q
T
F
S
M
E
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
I256
T
T
T
S
N
T
A
I
T
T
T
T
V
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
N612
T
T
A
T
T
T
L
N
S
H
N
N
R
N
H
Honey Bee
Apis mellifera
XP_624285
300
34327
L255
S
D
I
A
Q
K
D
L
E
L
F
D
Q
I
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
F304
D
L
Q
T
D
M
L
F
D
P
Y
K
E
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
M375
S
S
Q
D
I
S
G
M
M
K
I
V
P
S
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
Y411
G
D
T
S
D
L
N
Y
L
Q
E
Q
V
G
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
0
93.3
20
N.A.
26.6
6.6
N.A.
20
6.6
13.3
6.6
N.A.
20
0
N.A.
20
P-Site Similarity:
100
33.3
100
46.6
N.A.
40
20
N.A.
26.6
20
40
40
N.A.
46.6
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
27
20
14
0
7
0
14
7
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
14
7
7
27
0
7
7
14
0
20
20
0
14
14
% D
% Glu:
0
7
0
0
20
0
7
0
7
0
7
7
14
0
27
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
7
7
7
0
0
% F
% Gly:
7
7
7
7
0
7
14
14
20
20
7
0
7
27
14
% G
% His:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% H
% Ile:
0
0
7
0
14
20
0
14
7
14
20
20
7
7
7
% I
% Lys:
0
0
0
0
0
7
0
0
0
14
0
7
0
0
0
% K
% Leu:
0
14
0
0
7
14
14
7
7
7
0
0
7
7
0
% L
% Met:
0
7
0
0
0
7
0
7
14
0
0
0
0
14
14
% M
% Asn:
0
0
0
0
7
0
7
7
0
0
7
7
0
7
0
% N
% Pro:
7
14
0
0
0
0
7
0
0
7
0
7
7
14
7
% P
% Gln:
0
0
14
7
7
0
7
0
0
14
0
7
7
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
27
27
27
27
0
14
34
20
14
7
14
7
20
7
7
% S
% Thr:
40
14
14
34
7
14
0
7
7
7
14
7
0
0
0
% T
% Val:
0
0
0
0
0
14
0
0
0
0
0
7
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _